Advises companies, boards of directors, and individuals in high-stakes commercial litigation and complex disputes
Represents clients in government investigations, internal investigations, and regulatory enforcement matters
Defends healthcare organizations in False Claims Act (FCA), fraud and abuse, and other healthcare enforcement proceedings
Matt Knowles advises companies, boards of directors and individuals in high-stakes commercial litigation as well as government and internal investigations. His work spans a broad range of litigation matters at the trial and appellate levels in federal and state courts across the country, including class actions and other complex matters. Matt also represents clients in investigations conducted by federal government agencies as well as state attorneys general.
Matt frequently represents companies and individuals in investigations and litigation under the False Claims Act. He also has substantial experience helping clients manage legal and reputational risk in crisis situations, including recent matters involving disease outbreaks at hospitals, allegations of misconduct at medical facilities and disputes involving educational institutions.
- Represented numerous hospitals, physicians’ groups, medical device manufacturers, and other healthcare entities in government investigations and litigation (at both the trial and appellate level) under the False Claims Act. This includes a recent False Claims Act appeal arising from allegations of medically unnecessary surgical procedures, in which Matt argued before the United States Court of Appeals for the Tenth Circuit. In particular, Matt specializes in False Claims Act matters and other enforcement proceedings involving hospitals, provider entities, laboratories, and controlled-substance prescribing.
- Helped to lead McDermott’s investigation into an outbreak of COVID-19 at the Holyoke Soldiers’ Home that led to the deaths of at least 76 veterans. The Governor of Massachusetts retained McDermott to investigate the tragedy, identify root causes, and make recommendations to prevent similar outbreaks. Matt coordinated a team of thirteen lawyers that worked around the clock to conduct 111 interviews and review 17,000 documents in a matter of weeks. The team’s work resulted in a public 176-page report and substantial legislative changes to ensure the future of the Soldiers’ Home and the safety of its residents.
- Defeated class certification and secured voluntary dismissal of all claims against a healthcare client in a case arising from one of the largest outbreaks of hepatitis C in the nation’s history. The matter began as an internal investigation and resulted in a favorable settlement for Matt’s client – by that point, the plaintiff in the case – on the eve of trial.
- Defeated a high-stakes claim against an agricultural co-op in the trial and appellate courts of California. Matt’s client moved to a new operating model, but an incumbent grower-member sued seeking extensive damages and to compel the co-op to abandon its new model. Matt briefed and argued three motions to dismiss the case, each of which was successful despite a plaintiff-friendly forum and relaxed pleading standards in state court. When the plaintiff appealed, Matt briefed and argued the matter before the California Courts of Appeal, which affirmed his client’s victory on all counts.
- Best Lawyers in America, Commercial Litigation (2026-2027), Litigation – Health Care, 2026-2027
- Legal 500 US, Recommended Lawyer, 2023-2025
- Chambers USA, Litigation, 2024-2026
- Massachusetts Lawyers Weekly, “Up & Coming Lawyer,” 2017
- Massachusetts Standing Advisory Committee on the Rules of Civil Procedure, Committee Member, 2026
- Business and Commercial Litigation Section of the Boston Bar Association, Steering Committee Member, 2025-2026
- Law360, Massachusetts Editorial Board, 2022
- Harvard Law School, JD, cum laude
- Harvard College, AB, cum laude
- Massachusetts
- Supreme Court of the United States
- US Court of Appeals for the Federal Circuit
- US Court of Appeals for the First Circuit
- US Court of Appeals for the Third Circuit
- US Court of Appeals for the Tenth Circuit
- US Court of Appeals for the Eleventh Circuit
- US Court of Federal Claims
- US District Court for the Central District of Illinois
- US District Court for the District of Massachusetts